Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging

Abdul Haseeb; Beko Mesic; Jörgen Samuelsson

doi:doi:10.11648/j.am.20241301.11

Research Article |

| Peer-Reviewed

Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging

Abdul Haseeb, Beko Mesic^*, Jörgen Samuelsson

Published in Advances in Materials (Volume 13, Issue 1)

Received: 27 November 2023 Accepted: 21 December 2023 Published: 8 January 2024

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Antimicrobial packaging has emerged as one of the most effective packaging systems in prolonging shelf life and maintaining food quality. For an effective system, a controlled and gradual release of antimicrobial agents into food items over time is crucial. Modified Calcium Carbonate (MCC), known for its diverse applications in pharmaceuticals and drug delivery, could act as a potential carrier for such agents in packaging. In this context, a fundamental study of the adsorption of two reference antimicrobial agents, Benzoic Acid (BA) and Thymol (TM), was carried on MCC and silica in solvents of different polarities. Based on the initial adsorption study, the adsorption isotherms of the two compounds were acquired by batch method in different solvents and then the adsorption data was modeled using adsorption isotherm models. Here, we found that n-Heptane was the most efficient solvent for both BA and TM on both adsorbents. From the outcome of the adsorption study, a model dispersion coating was prepared by mixing MCC (loaded with BA) with latex binder. Then the effect of latex binder on the rate of BA release from MMC was investigated by conducting desorption study using simulated body fluid as the desorbent solution at 4°C, comparing MCC with and without latex. It was found that the release rate of BA from our latex model dispersion coating was 31 time slower than that of MMC without latex. This indicates the potential application of our model dispersion coating in antimicrobial packaging.

Published in	Advances in Materials (Volume 13, Issue 1)
DOI	10.11648/j.am.20241301.11
Page(s)	1-9
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Antimicrobial Packaging, Modified Calcium Carbonate, Silica, Benzoic Acid, Thymol, Adsorption, Desorption, Adsorbent

References

[1]	X. Sun, J. Wang, M. Dong, H. Zhang, L. Li, L. Wang, Food spoilage, bioactive food fresh-keeping films and functional edible coatings: Research status, existing problems and development trend, Trends in Food Science & Technology. 119 (2022) 122–132. https://doi.org/10.1016/j.tifs.2021.12.004.
[2]	S. M. Abdel-Aziz, M. M. Asker, A. A. Keera, M. G. Mahmoud, Microbial food spoilage: control strategies for shelf-life extension, Microbes in Food and Health. (2016) 239–264.
[3]	J. H. J. H. in’t Veld, Microbial and biochemical spoilage of foods: an overview, International Journal of Food Microbiology. 33 (1996) 1–18. https://doi.org/10.1016/0168-1605(96)01139-7.
[4]	S.-Y. Sung, L. T. Sin, T.-T. Tee, S.-T. Bee, A. R. Rahmat, W. Rahman, A.-C. Tan, M. Vikhraman, Antimicrobial agents for food packaging applications, Trends in Food Science & Technology. 33 (2013) 110–123.
[5]	S. Quintavalla, L. Vicini, Antimicrobial food packaging in meat industry, Meat Science. 62 (2002) 373–380. https://doi.org/10.1016/S0309-1740(02)00121-3.
[6]	A. KD, K. K. Jabo, Determination of Traditional and Biologically Viable Methods for Food Preservation: A Review, J Vet Heal Sci. 3 (2022) 384–389.
[7]	G. L. Robertson, Food packaging and shelf life: a practical guide, CRC Press, 2009.
[8]	C. N. Cutter, Microbial control by packaging: a review, Critical Reviews in Food Science and Nutrition. 42 (2002) 151–161.
[9]	S. Naqash, F. Naqash, S. Fayaz, S. Khan, B. N. Dar, H. A. Makroo, Application of Natural Antimicrobial Agents in Different Food Packaging Systems and Their Role in Shelf-life Extension of Food: A Review, Journal of Packaging Technology and Research. 6 (2022) 73–89.
[10]	R. Chawla, S. Sivakumar, H. Kaur, Antimicrobial edible films in food packaging: Current scenario and recent nanotechnological advancements- a review, Carbohydrate Polymer Technologies and Applications. 2 (2021) 100024. https://doi.org/10.1016/j.carpta.2020.100024.
[11]	L. Kuai, F. Liu, B.-S. Chiou, R.J. Avena-Bustillos, T. H. McHugh, F. Zhong, Controlled release of antioxidants from active food packaging: A review, Food Hydrocolloids. 120 (2021) 106992. https://doi.org/10.1016/j.foodhyd.2021.106992.
[12]	P. Widsten, B. B. Mesic, C. D. Cruz, G. C. Fletcher, M. A. Chycka, Inhibition of foodborne bacteria by antibacterial coatings printed onto food packaging films, Journal of Food Science and Technology. 54 (2017) 2379–2386.
[13]	N. Rüegg, S. R. Teixeira, B. M. Beck, F. W. Monnard, R. Menard, S. Yildirim, Application of antimicrobial packaging based on modified calcium carbonate and EOs for RTE meat products, Food Packaging and Shelf Life. 34 (2022) 100982.
[14]	J. H. Han, 4 - Antimicrobial food packaging, in: R. Ahvenainen (Ed.), Novel Food Packaging Techniques, Woodhead Publishing, 2003: pp. 50–70. https://doi.org/10.1533/9781855737020.1.50.
[15]	S. Ahmed, D. E. Sameen, R. Lu, R. Li, J. Dai, W. Qin, Y. Liu, Research progress on antimicrobial materials for food packaging, Critical Reviews in Food Science and Nutrition. 62 (2022) 3088–3102.
[16]	P. Suppakul, J. Miltz, K. Sonneveld, S. W. Bigger, Active packaging technologies with an emphasis on antimicrobial packaging and its applications, Journal of Food Science. 68 (2003) 408–420.
[17]	R. D. Joerger, Antimicrobial films for food applications: a quantitative analysis of their effectiveness, Packaging Technology and Science: An International Journal. 20 (2007) 231–273.
[18]	H. Brown, J. Williams, M. Kirwan, Packaged product quality and shelf life, Food and Beverage Packaging Technology. (2011) 59–83.
[19]	P. a. C. Gane, C. J. Ridgway, E. Barceló, Analysis of pore structure enables improved tablet delivery systems, Powder Technology. 169 (2021) 77. https://www.academia.edu/16310239/Analysis_of_pore_structure_enables_improved_tablet_delivery_systems (accessed September 9, 2021).
[20]	M. Fujiwara, K. Shiokawa, K. Morigaki, Y. Zhu, Y. Nakahara, Calcium carbonate microcapsules encapsulating biomacromolecules, Chemical Engineering Journal. 137 (2008) 14–22. https://doi.org/10.1016/j.cej.2007.09.010.
[21]	Y. Ueno, H. Futagawa, Y. Takagi, A. Ueno, Y. Mizushima, Drug-incorporating calcium carbonate nanoparticles for a new delivery system, Journal of Controlled Release. 103 (2005) 93–98. https://doi.org/10.1016/j.jconrel.2004.11.015.
[22]	B. Röcker, G. Mäder, F. W. Monnard, M. Jancikova, M. Welker, J. Schoelkopf, S. Yildirim, Evaluation of the potential of modified calcium carbonate as a carrier for unsaturated fatty acids in oxygen scavenging applications, Materials. 14 (2021) 5000.
[23]	Y. Wang, A. Liu, R. Ye, X. Li, Y. Han, C. Liu, The production of gelatin-calcium carbonate composite films with different antioxidants, International Journal of Food Properties. 18 (2015) 2442–2456.
[24]	G. Guiochon, A. Felinger, D. G. Shirazi, Fundamentals of preparative and nonlinear chromatography, Elsevier, 2006.
[25]	T. Shibamoto, L. F. Bjeldanes, Chapter 9 - Food Additives, in: Introduction to Food Toxicology, Academic Press, 1993: p. Pages 157-182. https://doi.org/10.1016/B978-0-08-092577-6.50014-9. (https://www.sciencedirect.com/science/article/pii/B9780080925776500149).
[26]	A. Heydari, J. Hadian, H. Esmaeili, M. R. Kanani, M. H. Mirjalili, A. Sarkhosh, Introduction of TMmus daenensis into cultivation: Analysis of agro-morphological, phytochemical and genetic diversity of cultivated clones, Industrial Crops and Products. 131 (2019) 14–24.
[27]	A. Marchese, I. E. Orhan, M. Daglia, R. Barbieri, A. Di Lorenzo, S. F. Nabavi, O. Gortzi, M. Izadi, S. M. Nabavi, Antibacterial and antifungal activities of TM: A brief review of the literature, Food Chemistry. 210 (2016) 402–414.
[28]	B. J. Stanley, G. Guiochon, Numerical estimation of adsorption energy distributions from adsorption isotherm data with the expectation-maximization method, The Journal of Physical Chemistry. 97 (1993) 8098–8104.
[29]	T. Kokubo, H. Kushitani, S. Sakka, T. Kitsugi and T. Yamamuro, Solutions able to reproduce in vivo surface-structure changes in bioactive glass-ceramic A-W, J. Biomed. Mater. Res., 24, 721-734 (1990).
[30]	C. L. Levy, G. P. Matthews, G. M. Laudone, S. Beckett, A. Turner, J. Schoelkopf, P. A. C. Gane, Mechanism of adsorption of actives onto microporous functionalised calcium carbonate (FCC), Adsorption. 23 (2017) 603–612. https://doi.org/10.1007/s10450-017-9880-7.
[31]	Tobi Fadiji, Mahdi Rashvand, Michael O. Daramola and Samuel A. Iwarere, A Review on Antimicrobial Packaging for Extending the Shelf Life of Food. In Processes 2023, 11, 590. https://doi.org/10.3390/pr11020590

Cite This Article

Plain Text BibTeX RIS

APA Style

Haseeb, A., Mesic, B., Samuelsson, J. (2024). Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging. Advances in Materials, 13(1), 1-9. https://doi.org/10.11648/j.am.20241301.11

Copy | Download

ACS Style

Haseeb, A.; Mesic, B.; Samuelsson, J. Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging. Adv. Mater. 2024, 13(1), 1-9. doi: 10.11648/j.am.20241301.11

Copy | Download

AMA Style

Haseeb A, Mesic B, Samuelsson J. Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging. Adv Mater. 2024;13(1):1-9. doi: 10.11648/j.am.20241301.11

Copy | Download

@article{10.11648/j.am.20241301.11,
  author = {Abdul Haseeb and Beko Mesic and Jörgen Samuelsson},
  title = {Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging},
  journal = {Advances in Materials},
  volume = {13},
  number = {1},
  pages = {1-9},
  doi = {10.11648/j.am.20241301.11},
  url = {https://doi.org/10.11648/j.am.20241301.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.am.20241301.11},
  abstract = {Antimicrobial packaging has emerged as one of the most effective packaging systems in prolonging shelf life and maintaining food quality. For an effective system, a controlled and gradual release of antimicrobial agents into food items over time is crucial. Modified Calcium Carbonate (MCC), known for its diverse applications in pharmaceuticals and drug delivery, could act as a potential carrier for such agents in packaging. In this context, a fundamental study of the adsorption of two reference antimicrobial agents, Benzoic Acid (BA) and Thymol (TM), was carried on MCC and silica in solvents of different polarities. Based on the initial adsorption study, the adsorption isotherms of the two compounds were acquired by batch method in different solvents and then the adsorption data was modeled using adsorption isotherm models. Here, we found that n-Heptane was the most efficient solvent for both BA and TM on both adsorbents. From the outcome of the adsorption study, a model dispersion coating was prepared by mixing MCC (loaded with BA) with latex binder. Then the effect of latex binder on the rate of BA release from MMC was investigated by conducting desorption study using simulated body fluid as the desorbent solution at 4°C, comparing MCC with and without latex. It was found that the release rate of BA from our latex model dispersion coating was 31 time slower than that of MMC without latex. This indicates the potential application of our model dispersion coating in antimicrobial packaging.
},
 year = {2024}
}

Copy | Download

TY  - JOUR
T1  - Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging
AU  - Abdul Haseeb
AU  - Beko Mesic
AU  - Jörgen Samuelsson
Y1  - 2024/01/08
PY  - 2024
N1  - https://doi.org/10.11648/j.am.20241301.11
DO  - 10.11648/j.am.20241301.11
T2  - Advances in Materials
JF  - Advances in Materials
JO  - Advances in Materials
SP  - 1
EP  - 9
PB  - Science Publishing Group
SN  - 2327-252X
UR  - https://doi.org/10.11648/j.am.20241301.11
AB  - Antimicrobial packaging has emerged as one of the most effective packaging systems in prolonging shelf life and maintaining food quality. For an effective system, a controlled and gradual release of antimicrobial agents into food items over time is crucial. Modified Calcium Carbonate (MCC), known for its diverse applications in pharmaceuticals and drug delivery, could act as a potential carrier for such agents in packaging. In this context, a fundamental study of the adsorption of two reference antimicrobial agents, Benzoic Acid (BA) and Thymol (TM), was carried on MCC and silica in solvents of different polarities. Based on the initial adsorption study, the adsorption isotherms of the two compounds were acquired by batch method in different solvents and then the adsorption data was modeled using adsorption isotherm models. Here, we found that n-Heptane was the most efficient solvent for both BA and TM on both adsorbents. From the outcome of the adsorption study, a model dispersion coating was prepared by mixing MCC (loaded with BA) with latex binder. Then the effect of latex binder on the rate of BA release from MMC was investigated by conducting desorption study using simulated body fluid as the desorbent solution at 4°C, comparing MCC with and without latex. It was found that the release rate of BA from our latex model dispersion coating was 31 time slower than that of MMC without latex. This indicates the potential application of our model dispersion coating in antimicrobial packaging.

VL  - 13
IS  - 1
ER  -

Copy | Download

Author Information

Abdul Haseeb

Department of Engineering and Chemical Sciences, Karlstad University, Karlstad, Sweden

Contact Email
Beko Mesic

Department of Engineering and Chemical Sciences, Karlstad University, Karlstad, Sweden

Contact Email
Jörgen Samuelsson

Department of Engineering and Chemical Sciences, Karlstad University, Karlstad, Sweden

Contact Email

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Haseeb, A., Mesic, B., Samuelsson, J. (2024). Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging. Advances in Materials, 13(1), 1-9. https://doi.org/10.11648/j.am.20241301.11

Copy | Download

ACS Style

Haseeb, A.; Mesic, B.; Samuelsson, J. Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging. Adv. Mater. 2024, 13(1), 1-9. doi: 10.11648/j.am.20241301.11

Copy | Download

AMA Style

Haseeb A, Mesic B, Samuelsson J. Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging. Adv Mater. 2024;13(1):1-9. doi: 10.11648/j.am.20241301.11

Copy | Download

@article{10.11648/j.am.20241301.11,
  author = {Abdul Haseeb and Beko Mesic and Jörgen Samuelsson},
  title = {Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging},
  journal = {Advances in Materials},
  volume = {13},
  number = {1},
  pages = {1-9},
  doi = {10.11648/j.am.20241301.11},
  url = {https://doi.org/10.11648/j.am.20241301.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.am.20241301.11},
  abstract = {Antimicrobial packaging has emerged as one of the most effective packaging systems in prolonging shelf life and maintaining food quality. For an effective system, a controlled and gradual release of antimicrobial agents into food items over time is crucial. Modified Calcium Carbonate (MCC), known for its diverse applications in pharmaceuticals and drug delivery, could act as a potential carrier for such agents in packaging. In this context, a fundamental study of the adsorption of two reference antimicrobial agents, Benzoic Acid (BA) and Thymol (TM), was carried on MCC and silica in solvents of different polarities. Based on the initial adsorption study, the adsorption isotherms of the two compounds were acquired by batch method in different solvents and then the adsorption data was modeled using adsorption isotherm models. Here, we found that n-Heptane was the most efficient solvent for both BA and TM on both adsorbents. From the outcome of the adsorption study, a model dispersion coating was prepared by mixing MCC (loaded with BA) with latex binder. Then the effect of latex binder on the rate of BA release from MMC was investigated by conducting desorption study using simulated body fluid as the desorbent solution at 4°C, comparing MCC with and without latex. It was found that the release rate of BA from our latex model dispersion coating was 31 time slower than that of MMC without latex. This indicates the potential application of our model dispersion coating in antimicrobial packaging.
},
 year = {2024}
}

Copy | Download

TY  - JOUR
T1  - Fundamental Investigation of the Adsorption of Antimicrobial Agents on Modified Calcium Carbonate and Silica and Its Potential Application in Food Packaging
AU  - Abdul Haseeb
AU  - Beko Mesic
AU  - Jörgen Samuelsson
Y1  - 2024/01/08
PY  - 2024
N1  - https://doi.org/10.11648/j.am.20241301.11
DO  - 10.11648/j.am.20241301.11
T2  - Advances in Materials
JF  - Advances in Materials
JO  - Advances in Materials
SP  - 1
EP  - 9
PB  - Science Publishing Group
SN  - 2327-252X
UR  - https://doi.org/10.11648/j.am.20241301.11
AB  - Antimicrobial packaging has emerged as one of the most effective packaging systems in prolonging shelf life and maintaining food quality. For an effective system, a controlled and gradual release of antimicrobial agents into food items over time is crucial. Modified Calcium Carbonate (MCC), known for its diverse applications in pharmaceuticals and drug delivery, could act as a potential carrier for such agents in packaging. In this context, a fundamental study of the adsorption of two reference antimicrobial agents, Benzoic Acid (BA) and Thymol (TM), was carried on MCC and silica in solvents of different polarities. Based on the initial adsorption study, the adsorption isotherms of the two compounds were acquired by batch method in different solvents and then the adsorption data was modeled using adsorption isotherm models. Here, we found that n-Heptane was the most efficient solvent for both BA and TM on both adsorbents. From the outcome of the adsorption study, a model dispersion coating was prepared by mixing MCC (loaded with BA) with latex binder. Then the effect of latex binder on the rate of BA release from MMC was investigated by conducting desorption study using simulated body fluid as the desorbent solution at 4°C, comparing MCC with and without latex. It was found that the release rate of BA from our latex model dispersion coating was 31 time slower than that of MMC without latex. This indicates the potential application of our model dispersion coating in antimicrobial packaging.

VL  - 13
IS  - 1
ER  -

Copy | Download