Bruceaantidysenterica (abalo in Amharic) is a medicinal plant widely used in traditional medicine for treatment of several diseases and ailments. This study aimed to investigate the classes of the phytochemical constituents of the leaves of Bruceaantidysenterica extracted with the solvents of petroleum ether, ethyl acetate, and methanol. The crud extract evaluated their antioxidant and antimicrobial activities. Qualitative phytochemical screening of the leaves of this plant indicated the presence of alkaloids, flavonoids, phenols, quinones, steroids, terpenoids, saponins, tannins and cumaroins. Quantitative analysis of the leaves of Bruceaantidysenterica revealed that the total phenolic content, expressed as gallic acid equivalent, ranged from 28.5 to 120.06 mg/g of dry weight of extracts. Likewise, the total flavonoid content of the extract, expressed as quercetin equivalent, varied from 26.05 to 83.663 mg/g of dry weight of extracts. All extracts showed antioxidant and antimicrobial activity. As seen from ferric reducing antioxidant power (FRAP) assay, methanol and ethyl acetate extracts of the leaves of Bruceaantidysenterica showed the highest total reducing power while petroleum ether extract exhibited the lowest total reducing power. Furthermore, all the extracts were tested against two gram positive bacteria (Staphylococcus aureus, Streptococcus pyogene) and two gram negative bacteria (Escherichia coli, k. pneumonia) bacteria by Kirby-Bauer standard disc diffusion method. Antibacterial effects of leaves extracts of bruceaantidysenterica showed different degrees of inhibition against both Gram positive and Gram negative bacteria. The methanol and ethyl acetate extracts showed higher antibacterial activity than petroleum ether extracts.
| Published in | Modern Chemistry (Volume 11, Issue 1) |
| DOI | 10.11648/j.mc.20231101.13 |
| Page(s) | 34-42 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2023. Published by Science Publishing Group |
Bruceaantidysenterica, Antioxidant Activity, Phytochemical Constituent, Antibacterial Activity
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APA Style
Liyew Yizengaw Yitayih, Thevabakthi Siluvai Muthu Arul Jeevan, Solomon Libsu Bikilla, Tesfahun Dagnaw Demelash. (2023). Determination of the Antibacterial and Antioxidant Activity of Crude Extract of Bruceaantidysenterica Leaves. Modern Chemistry, 11(1), 34-42. https://doi.org/10.11648/j.mc.20231101.13
ACS Style
Liyew Yizengaw Yitayih; Thevabakthi Siluvai Muthu Arul Jeevan; Solomon Libsu Bikilla; Tesfahun Dagnaw Demelash. Determination of the Antibacterial and Antioxidant Activity of Crude Extract of Bruceaantidysenterica Leaves. Mod. Chem. 2023, 11(1), 34-42. doi: 10.11648/j.mc.20231101.13
AMA Style
Liyew Yizengaw Yitayih, Thevabakthi Siluvai Muthu Arul Jeevan, Solomon Libsu Bikilla, Tesfahun Dagnaw Demelash. Determination of the Antibacterial and Antioxidant Activity of Crude Extract of Bruceaantidysenterica Leaves. Mod Chem. 2023;11(1):34-42. doi: 10.11648/j.mc.20231101.13
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Download@article{10.11648/j.mc.20231101.13,
author = {Liyew Yizengaw Yitayih and Thevabakthi Siluvai Muthu Arul Jeevan and Solomon Libsu Bikilla and Tesfahun Dagnaw Demelash},
title = {Determination of the Antibacterial and Antioxidant Activity of Crude Extract of Bruceaantidysenterica Leaves},
journal = {Modern Chemistry},
volume = {11},
number = {1},
pages = {34-42},
doi = {10.11648/j.mc.20231101.13},
url = {https://doi.org/10.11648/j.mc.20231101.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.mc.20231101.13},
abstract = {Bruceaantidysenterica (abalo in Amharic) is a medicinal plant widely used in traditional medicine for treatment of several diseases and ailments. This study aimed to investigate the classes of the phytochemical constituents of the leaves of Bruceaantidysenterica extracted with the solvents of petroleum ether, ethyl acetate, and methanol. The crud extract evaluated their antioxidant and antimicrobial activities. Qualitative phytochemical screening of the leaves of this plant indicated the presence of alkaloids, flavonoids, phenols, quinones, steroids, terpenoids, saponins, tannins and cumaroins. Quantitative analysis of the leaves of Bruceaantidysenterica revealed that the total phenolic content, expressed as gallic acid equivalent, ranged from 28.5 to 120.06 mg/g of dry weight of extracts. Likewise, the total flavonoid content of the extract, expressed as quercetin equivalent, varied from 26.05 to 83.663 mg/g of dry weight of extracts. All extracts showed antioxidant and antimicrobial activity. As seen from ferric reducing antioxidant power (FRAP) assay, methanol and ethyl acetate extracts of the leaves of Bruceaantidysenterica showed the highest total reducing power while petroleum ether extract exhibited the lowest total reducing power. Furthermore, all the extracts were tested against two gram positive bacteria (Staphylococcus aureus, Streptococcus pyogene) and two gram negative bacteria (Escherichia coli, k. pneumonia) bacteria by Kirby-Bauer standard disc diffusion method. Antibacterial effects of leaves extracts of bruceaantidysenterica showed different degrees of inhibition against both Gram positive and Gram negative bacteria. The methanol and ethyl acetate extracts showed higher antibacterial activity than petroleum ether extracts.},
year = {2023}
}
TY - JOUR T1 - Determination of the Antibacterial and Antioxidant Activity of Crude Extract of Bruceaantidysenterica Leaves AU - Liyew Yizengaw Yitayih AU - Thevabakthi Siluvai Muthu Arul Jeevan AU - Solomon Libsu Bikilla AU - Tesfahun Dagnaw Demelash Y1 - 2023/03/31 PY - 2023 N1 - https://doi.org/10.11648/j.mc.20231101.13 DO - 10.11648/j.mc.20231101.13 T2 - Modern Chemistry JF - Modern Chemistry JO - Modern Chemistry SP - 34 EP - 42 PB - Science Publishing Group SN - 2329-180X UR - https://doi.org/10.11648/j.mc.20231101.13 AB - Bruceaantidysenterica (abalo in Amharic) is a medicinal plant widely used in traditional medicine for treatment of several diseases and ailments. This study aimed to investigate the classes of the phytochemical constituents of the leaves of Bruceaantidysenterica extracted with the solvents of petroleum ether, ethyl acetate, and methanol. The crud extract evaluated their antioxidant and antimicrobial activities. Qualitative phytochemical screening of the leaves of this plant indicated the presence of alkaloids, flavonoids, phenols, quinones, steroids, terpenoids, saponins, tannins and cumaroins. Quantitative analysis of the leaves of Bruceaantidysenterica revealed that the total phenolic content, expressed as gallic acid equivalent, ranged from 28.5 to 120.06 mg/g of dry weight of extracts. Likewise, the total flavonoid content of the extract, expressed as quercetin equivalent, varied from 26.05 to 83.663 mg/g of dry weight of extracts. All extracts showed antioxidant and antimicrobial activity. As seen from ferric reducing antioxidant power (FRAP) assay, methanol and ethyl acetate extracts of the leaves of Bruceaantidysenterica showed the highest total reducing power while petroleum ether extract exhibited the lowest total reducing power. Furthermore, all the extracts were tested against two gram positive bacteria (Staphylococcus aureus, Streptococcus pyogene) and two gram negative bacteria (Escherichia coli, k. pneumonia) bacteria by Kirby-Bauer standard disc diffusion method. Antibacterial effects of leaves extracts of bruceaantidysenterica showed different degrees of inhibition against both Gram positive and Gram negative bacteria. The methanol and ethyl acetate extracts showed higher antibacterial activity than petroleum ether extracts. VL - 11 IS - 1 ER -
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