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The Pattern of Poisoning and It’s Management and Outcome in a Tertiary Care Hospital, Bangladesh: An Observational Study

Received: 13 October 2021     Accepted: 23 November 2021     Published: 2 December 2021
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Abstract

Introduction: In 2020, during the epidemic of corona, this study was done to see the patterns of the cases of Poisoning, in a tertiary hospital in Dhaka city. Poisoning exposure in adults and teenagers are more often intentional (recreational or suicidal), may involve multiple agents, which are commonly pharmaceuticals, and may be delayed in diagnosis and treatment. Objective: To assess the pattern of cases of poisoning found in 2020 January to February 2021, management and outcome. Methods: This Observational study was performed at Square Hospital, Dhaka, exclusively over 40 poisoned patients. It included the cases of poisoning, admitted in 2020 January to 2021 February. The collected cases are of commuter poisoning, suicidal poisoning, methyl alcohol poisoning and poisoning with sedative agents by housemaids. All these cases were admitted initially in the ICU after the initial management given in the Department of emergency. Results: In total we managed 40 cases. Among the 22 cases of suicidal poisoning, sedative poisoning was 10, antidepressant were 4, anti-schizophrenic was 1, anticonvulsant were 2, paracetamol poisoning was 1, propranolol poisoning 1. We found 1 case of paracetamol poisoning, 1 case of mixed oral anti diabetic agents (dapagliflozin, sitagliptin, glimeperide, added with metformin) 1 case of unknown poisoning (as blood level of drugs revealed nothing may be because of late presentation). We also found 12 cases of methanol poisoning and 6 patients of unknown poisoning. Among them 3 patients was poisoned by housemaid, 3 patients were cases of street poisoning. Benzodiazepine was found in all these 6 cases. In other studies it is found that, street poisoning by sedative hypnotic drugs were the highest percentage (37%) and all were male. E. Most of the victims of street poisoning were business man (67.56%) rest were normal/domestic travelers (16.2%) and few were service holders (10.81%). E. There were financial loss (loss of money or expensive things) of the patients. In analysis of the causes behind suicidal poisoning in other studies it is also found that, 57% were due to familial disharmony, 23% were poverty related, 15% were due to failure in affairs, 11% were due to failure in the examination, 4% were due to sexual abuse and 5% due to chronic illness and unknown cause. E. Conclusion: In the year of 2020, January to December, it was observed that the cases of alcohol poisoning was reduced. But in 2021 January to February there was a rapid rise of cases (8 cases in 2 months, the number we found in whole year of 2020 was only 4).

Published in Science Journal of Clinical Medicine (Volume 10, Issue 4)
DOI 10.11648/j.sjcm.20211004.18
Page(s) 126-130
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Poisoning, Suicidal Poisoning, Trend, Street Poisoning.

References
[1] Sharma R, Neelanjana, Rawat N, Panwar N. Mortality and morbidity associated with acute poisoning cases in north-east India: A retrospective study. J Family Med Prim Care. 2019; 8 (6): 2068-2072. doi: 10.4103/jfmpc.jfmpc_237_19.
[2] Singh GK, Lokhande A, Azuine RE. Global Inequalities in Youth Mortality, 2007-2012. Int J MCH AIDS. 2015; 3 (1): 53-62.
[3] Anthony L, Kulkarni C. Patterns of poisoning and drug overdosage and their outcome among in-patients admitted to the emergency medicine department of a tertiary care hospital. Indian J Crit Care Med. 2012; 16 (3): 130-135. doi: 10.4103/0972-5229.102070.
[4] Anthony, Leena, and Chanda Kulkarni. “Patterns of poisoning and drug overdosage and their outcome among in-patients admitted to the emergency medicine department of a tertiary care hospital.” Indian journal of critical care medicine: peer-reviewed, official publication of Indian Society of Critical Care Medicine vol. 16, 3 (2012): 130-5. doi: 10.4103/0972-5229.102070.
[5] Lee, HL., Lin, HJ., Yeh, S. TY. et al. Presentations of patients of poisoning and predictors of poisoning-related fatality: Findings from a hospital-based prospective study. BMC Public Health 8, 7 (2008). https://doi.org/10.1186/1471-2458-8-7.
[6] Barceloux DG, Bond GR, Krenzelok EP, Cooper H, Vale JA; American Academy of Clinical Toxicology Ad Hoc Committee on the Treatment Guidelines for Methanol Poisoning. American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoning. J Toxicol Clin Toxicol. 2002; 40 (4): 415-446. Doi: 10.1081/clt-120006745.
[7] Shadnia S, Rahimi M, Soltaninejad K, Nilli A. Role of clinical and paraclinical manifestations of methanol poisoning in outcome prediction. J Res Med Sci. 2013; 18 (10): 865-869.
[8] MAR Howlader, MZ Hossain, MG Morshed, H Begum, MH Sardar, MH Uddin, KAK Azad. Changing trends of poisoning in Bangladesh. Journal of Dhaka Medical College. 2011, vol 20 No 1. DOI: https://doi. Org/10.3329/jdmc.v20i1.8582
[9] Majumder MM, Basher A, Faiz MA, et al. Criminal poisoning of commuters in Bangladesh: prospective and retrospective study. Forensic Sci Int. 2008; 180 (1): 10-16. doi: 10.1016/j.forsciint.2008.06.016.
[10] Sasanami M, Yamada T, Obara T, Nakao A, Naito H. Oral Ethanol Treatment for Ethylene Glycol Intoxication. Cureus. 2020; 12 (12): e12268. Published 2020 Dec 25. doi: 10.7759/cureus.12268.
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    Rozana Rouf, Raihan Rabbani, Tahmina Rahman, Pratik Dewan, Shihan Mahmud Redwanul Huq. (2021). The Pattern of Poisoning and It’s Management and Outcome in a Tertiary Care Hospital, Bangladesh: An Observational Study. Science Journal of Clinical Medicine, 10(4), 126-130. https://doi.org/10.11648/j.sjcm.20211004.18

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    Rozana Rouf; Raihan Rabbani; Tahmina Rahman; Pratik Dewan; Shihan Mahmud Redwanul Huq. The Pattern of Poisoning and It’s Management and Outcome in a Tertiary Care Hospital, Bangladesh: An Observational Study. Sci. J. Clin. Med. 2021, 10(4), 126-130. doi: 10.11648/j.sjcm.20211004.18

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    AMA Style

    Rozana Rouf, Raihan Rabbani, Tahmina Rahman, Pratik Dewan, Shihan Mahmud Redwanul Huq. The Pattern of Poisoning and It’s Management and Outcome in a Tertiary Care Hospital, Bangladesh: An Observational Study. Sci J Clin Med. 2021;10(4):126-130. doi: 10.11648/j.sjcm.20211004.18

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  • @article{10.11648/j.sjcm.20211004.18,
      author = {Rozana Rouf and Raihan Rabbani and Tahmina Rahman and Pratik Dewan and Shihan Mahmud Redwanul Huq},
      title = {The Pattern of Poisoning and It’s Management and Outcome in a Tertiary Care Hospital, Bangladesh: An Observational Study},
      journal = {Science Journal of Clinical Medicine},
      volume = {10},
      number = {4},
      pages = {126-130},
      doi = {10.11648/j.sjcm.20211004.18},
      url = {https://doi.org/10.11648/j.sjcm.20211004.18},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20211004.18},
      abstract = {Introduction: In 2020, during the epidemic of corona, this study was done to see the patterns of the cases of Poisoning, in a tertiary hospital in Dhaka city. Poisoning exposure in adults and teenagers are more often intentional (recreational or suicidal), may involve multiple agents, which are commonly pharmaceuticals, and may be delayed in diagnosis and treatment. Objective: To assess the pattern of cases of poisoning found in 2020 January to February 2021, management and outcome. Methods: This Observational study was performed at Square Hospital, Dhaka, exclusively over 40 poisoned patients. It included the cases of poisoning, admitted in 2020 January to 2021 February. The collected cases are of commuter poisoning, suicidal poisoning, methyl alcohol poisoning and poisoning with sedative agents by housemaids. All these cases were admitted initially in the ICU after the initial management given in the Department of emergency. Results: In total we managed 40 cases. Among the 22 cases of suicidal poisoning, sedative poisoning was 10, antidepressant were 4, anti-schizophrenic was 1, anticonvulsant were 2, paracetamol poisoning was 1, propranolol poisoning 1. We found 1 case of paracetamol poisoning, 1 case of mixed oral anti diabetic agents (dapagliflozin, sitagliptin, glimeperide, added with metformin) 1 case of unknown poisoning (as blood level of drugs revealed nothing may be because of late presentation). We also found 12 cases of methanol poisoning and 6 patients of unknown poisoning. Among them 3 patients was poisoned by housemaid, 3 patients were cases of street poisoning. Benzodiazepine was found in all these 6 cases. In other studies it is found that, street poisoning by sedative hypnotic drugs were the highest percentage (37%) and all were male. E. Most of the victims of street poisoning were business man (67.56%) rest were normal/domestic travelers (16.2%) and few were service holders (10.81%). E. There were financial loss (loss of money or expensive things) of the patients. In analysis of the causes behind suicidal poisoning in other studies it is also found that, 57% were due to familial disharmony, 23% were poverty related, 15% were due to failure in affairs, 11% were due to failure in the examination, 4% were due to sexual abuse and 5% due to chronic illness and unknown cause. E. Conclusion: In the year of 2020, January to December, it was observed that the cases of alcohol poisoning was reduced. But in 2021 January to February there was a rapid rise of cases (8 cases in 2 months, the number we found in whole year of 2020 was only 4).},
     year = {2021}
    }
    

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    T1  - The Pattern of Poisoning and It’s Management and Outcome in a Tertiary Care Hospital, Bangladesh: An Observational Study
    AU  - Rozana Rouf
    AU  - Raihan Rabbani
    AU  - Tahmina Rahman
    AU  - Pratik Dewan
    AU  - Shihan Mahmud Redwanul Huq
    Y1  - 2021/12/02
    PY  - 2021
    N1  - https://doi.org/10.11648/j.sjcm.20211004.18
    DO  - 10.11648/j.sjcm.20211004.18
    T2  - Science Journal of Clinical Medicine
    JF  - Science Journal of Clinical Medicine
    JO  - Science Journal of Clinical Medicine
    SP  - 126
    EP  - 130
    PB  - Science Publishing Group
    SN  - 2327-2732
    UR  - https://doi.org/10.11648/j.sjcm.20211004.18
    AB  - Introduction: In 2020, during the epidemic of corona, this study was done to see the patterns of the cases of Poisoning, in a tertiary hospital in Dhaka city. Poisoning exposure in adults and teenagers are more often intentional (recreational or suicidal), may involve multiple agents, which are commonly pharmaceuticals, and may be delayed in diagnosis and treatment. Objective: To assess the pattern of cases of poisoning found in 2020 January to February 2021, management and outcome. Methods: This Observational study was performed at Square Hospital, Dhaka, exclusively over 40 poisoned patients. It included the cases of poisoning, admitted in 2020 January to 2021 February. The collected cases are of commuter poisoning, suicidal poisoning, methyl alcohol poisoning and poisoning with sedative agents by housemaids. All these cases were admitted initially in the ICU after the initial management given in the Department of emergency. Results: In total we managed 40 cases. Among the 22 cases of suicidal poisoning, sedative poisoning was 10, antidepressant were 4, anti-schizophrenic was 1, anticonvulsant were 2, paracetamol poisoning was 1, propranolol poisoning 1. We found 1 case of paracetamol poisoning, 1 case of mixed oral anti diabetic agents (dapagliflozin, sitagliptin, glimeperide, added with metformin) 1 case of unknown poisoning (as blood level of drugs revealed nothing may be because of late presentation). We also found 12 cases of methanol poisoning and 6 patients of unknown poisoning. Among them 3 patients was poisoned by housemaid, 3 patients were cases of street poisoning. Benzodiazepine was found in all these 6 cases. In other studies it is found that, street poisoning by sedative hypnotic drugs were the highest percentage (37%) and all were male. E. Most of the victims of street poisoning were business man (67.56%) rest were normal/domestic travelers (16.2%) and few were service holders (10.81%). E. There were financial loss (loss of money or expensive things) of the patients. In analysis of the causes behind suicidal poisoning in other studies it is also found that, 57% were due to familial disharmony, 23% were poverty related, 15% were due to failure in affairs, 11% were due to failure in the examination, 4% were due to sexual abuse and 5% due to chronic illness and unknown cause. E. Conclusion: In the year of 2020, January to December, it was observed that the cases of alcohol poisoning was reduced. But in 2021 January to February there was a rapid rise of cases (8 cases in 2 months, the number we found in whole year of 2020 was only 4).
    VL  - 10
    IS  - 4
    ER  - 

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Author Information
  • Department of Medicine, Square Hospital Limited, Dhaka, Bangladesh

  • Department of Medicine, Square Hospital Limited, Dhaka, Bangladesh

  • Department of Neuro Medicine, Square Hospital Limited, Dhaka, Bangladesh

  • Internal Medicine & Endocrinologist Department, Square Hospital Limited, Dhaka, Bangladesh

  • Internal Medicine & Critical Care Department, Square Hospital Limited, Dhaka, Bangladesh

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