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Essential Thrombocytosis Detected in Pregnancy: A Case Report

Received: 22 October 2021     Accepted: 11 December 2021     Published: 24 December 2021
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Abstract

Essential thrombocytosis is a myeloproliferative disease of unknown reason that causes progressive platelet overproduction, which this high counts of platelets appear to be associated with intravascular thrombosis and related event. There are several medications to prevent thrombosis formation in these patients, such as hydroxyurea, and aspirin. We do not have much information about the duration of the medication. Our case was a 28-year-old woman without any history of medical problem, who gave birth recently, presented to the emergency department with epigastric abdominal pain, nausea/vomiting, loss of appetite, chills and diarrhea. On initial examination, huge splenomegaly about 20 cm below the edge of the ribs in the midclavicular line were detected. All lab data were within normal ranges. Pregnancy behaves as a trigger for undiagnosed essential thrombosis in this patient. She underwent anticoagulant therapy which still continuous. It seems that pregnancy became a triggering factor for ET in our case to show up with the symptoms like thrombosis. There is lack of evidence about duration of treatment. We don’t know when we should stop the anticoagulant therapy or we should continue the medications lifelong. This issue should be considered as the basis of future studies.

Published in Science Journal of Clinical Medicine (Volume 10, Issue 4)
DOI 10.11648/j.sjcm.20211004.21
Page(s) 143-146
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Essential Thrombocytosis, Pregnancy, Anticoagulants, Myeloproliferative

References
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[7] Nissenblatt MJ, Gartenberg G, Lee ML, Sciorra LJ, Rose DV, Rajendra BR. Case Report: Essential Thrombocytosis with the Philadelphia Chromosome (Ph′). The American journal of the medical sciences. 1986; 291 (4): 276-9.
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[18] De Stefano V, Za T, Rossi E, Fiorini A, Ciminello A, Luzzi C, et al. Influence of the JAK2 V617F mutation and inherited thrombophilia on the thrombotic risk among patients with essential thrombocythemia. Haematologica. 2009; 94 (5): 733-7.
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Cite This Article
  • APA Style

    Behshad Pazooki, Ailar Ahangari. (2021). Essential Thrombocytosis Detected in Pregnancy: A Case Report. Science Journal of Clinical Medicine, 10(4), 143-146. https://doi.org/10.11648/j.sjcm.20211004.21

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    ACS Style

    Behshad Pazooki; Ailar Ahangari. Essential Thrombocytosis Detected in Pregnancy: A Case Report. Sci. J. Clin. Med. 2021, 10(4), 143-146. doi: 10.11648/j.sjcm.20211004.21

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    AMA Style

    Behshad Pazooki, Ailar Ahangari. Essential Thrombocytosis Detected in Pregnancy: A Case Report. Sci J Clin Med. 2021;10(4):143-146. doi: 10.11648/j.sjcm.20211004.21

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  • @article{10.11648/j.sjcm.20211004.21,
      author = {Behshad Pazooki and Ailar Ahangari},
      title = {Essential Thrombocytosis Detected in Pregnancy: A Case Report},
      journal = {Science Journal of Clinical Medicine},
      volume = {10},
      number = {4},
      pages = {143-146},
      doi = {10.11648/j.sjcm.20211004.21},
      url = {https://doi.org/10.11648/j.sjcm.20211004.21},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20211004.21},
      abstract = {Essential thrombocytosis is a myeloproliferative disease of unknown reason that causes progressive platelet overproduction, which this high counts of platelets appear to be associated with intravascular thrombosis and related event. There are several medications to prevent thrombosis formation in these patients, such as hydroxyurea, and aspirin. We do not have much information about the duration of the medication. Our case was a 28-year-old woman without any history of medical problem, who gave birth recently, presented to the emergency department with epigastric abdominal pain, nausea/vomiting, loss of appetite, chills and diarrhea. On initial examination, huge splenomegaly about 20 cm below the edge of the ribs in the midclavicular line were detected. All lab data were within normal ranges. Pregnancy behaves as a trigger for undiagnosed essential thrombosis in this patient. She underwent anticoagulant therapy which still continuous. It seems that pregnancy became a triggering factor for ET in our case to show up with the symptoms like thrombosis. There is lack of evidence about duration of treatment. We don’t know when we should stop the anticoagulant therapy or we should continue the medications lifelong. This issue should be considered as the basis of future studies.},
     year = {2021}
    }
    

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    AU  - Behshad Pazooki
    AU  - Ailar Ahangari
    Y1  - 2021/12/24
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    DO  - 10.11648/j.sjcm.20211004.21
    T2  - Science Journal of Clinical Medicine
    JF  - Science Journal of Clinical Medicine
    JO  - Science Journal of Clinical Medicine
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    SN  - 2327-2732
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    AB  - Essential thrombocytosis is a myeloproliferative disease of unknown reason that causes progressive platelet overproduction, which this high counts of platelets appear to be associated with intravascular thrombosis and related event. There are several medications to prevent thrombosis formation in these patients, such as hydroxyurea, and aspirin. We do not have much information about the duration of the medication. Our case was a 28-year-old woman without any history of medical problem, who gave birth recently, presented to the emergency department with epigastric abdominal pain, nausea/vomiting, loss of appetite, chills and diarrhea. On initial examination, huge splenomegaly about 20 cm below the edge of the ribs in the midclavicular line were detected. All lab data were within normal ranges. Pregnancy behaves as a trigger for undiagnosed essential thrombosis in this patient. She underwent anticoagulant therapy which still continuous. It seems that pregnancy became a triggering factor for ET in our case to show up with the symptoms like thrombosis. There is lack of evidence about duration of treatment. We don’t know when we should stop the anticoagulant therapy or we should continue the medications lifelong. This issue should be considered as the basis of future studies.
    VL  - 10
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Author Information
  • Department of Internal Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

  • Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran

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