Preventive Effects of A Mixture of Micronutrients with Antioxida-tive Properties on Experimentally Induced Prostate Hyperplasia

Torricelli P.; Ferorelli P.; De Martino A.; Antonelli F.; Beninati S.

doi:doi:10.11648/j.ajls.20130101.14

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Preventive Effects of A Mixture of Micronutrients with Antioxida-tive Properties on Experimentally Induced Prostate Hyperplasia

Torricelli P., Ferorelli P., De Martino A., Antonelli F., Beninati S.

Published in American Journal of Life Sciences (Volume 1, Issue 1)

Published: 20 February 2013

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Abstract

A mixture of antioxidants found in a commercial food supplement called Citozym (CIZ), showed a preventive capability on experimental prostate hyperplasia induced by testosterone propionate (TP) in C57BL6/N mice. Treatments by CIZ were given orally and started 10 days before the induction of prostate hyperplasia. TP significantly increased prostate size and weight ratio, and this induced increase was significantly inhibited in CIZ-treated mice in comparison with positive controls in a dose-dependent manner. We conclude that CIZ can prevent TP-induced prostate hyperplasia and therefore may be beneficial in the management of benign prostatic hyperplasia.

Published in	American Journal of Life Sciences (Volume 1, Issue 1)
DOI	10.11648/j.ajls.20130101.14
Page(s)	22-26
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2013. Published by Science Publishing Group

Keywords

Antioxidants, Micronutrients, Benign Prostatic Hyperplasia

References

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APA Style

Torricelli P., Ferorelli P., De Martino A., Antonelli F., Beninati S. (2013). Preventive Effects of A Mixture of Micronutrients with Antioxida-tive Properties on Experimentally Induced Prostate Hyperplasia. American Journal of Life Sciences, 1(1), 22-26. https://doi.org/10.11648/j.ajls.20130101.14

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ACS Style

Torricelli P.; Ferorelli P.; De Martino A.; Antonelli F.; Beninati S. Preventive Effects of A Mixture of Micronutrients with Antioxida-tive Properties on Experimentally Induced Prostate Hyperplasia. Am. J. Life Sci. 2013, 1(1), 22-26. doi: 10.11648/j.ajls.20130101.14

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AMA Style

Torricelli P., Ferorelli P., De Martino A., Antonelli F., Beninati S. Preventive Effects of A Mixture of Micronutrients with Antioxida-tive Properties on Experimentally Induced Prostate Hyperplasia. Am J Life Sci. 2013;1(1):22-26. doi: 10.11648/j.ajls.20130101.14

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@article{10.11648/j.ajls.20130101.14,
  author = {Torricelli P. and Ferorelli P. and De Martino A. and Antonelli F. and Beninati S.},
  title = {Preventive Effects of A Mixture of Micronutrients with Antioxida-tive Properties on Experimentally Induced Prostate Hyperplasia},
  journal = {American Journal of Life Sciences},
  volume = {1},
  number = {1},
  pages = {22-26},
  doi = {10.11648/j.ajls.20130101.14},
  url = {https://doi.org/10.11648/j.ajls.20130101.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.20130101.14},
  abstract = {A mixture of antioxidants found in a commercial food supplement called Citozym (CIZ), showed a preventive capability on experimental prostate hyperplasia induced by testosterone propionate (TP) in C57BL6/N mice. Treatments by CIZ were given orally and started 10 days before the induction of prostate hyperplasia. TP significantly increased prostate size and weight ratio, and this induced increase was significantly inhibited in CIZ-treated mice in comparison with positive controls in a dose-dependent manner. We conclude that CIZ can prevent TP-induced prostate hyperplasia and therefore may be beneficial in the management of benign prostatic hyperplasia.},
 year = {2013}
}

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TY  - JOUR
T1  - Preventive Effects of A Mixture of Micronutrients with Antioxida-tive Properties on Experimentally Induced Prostate Hyperplasia
AU  - Torricelli P.
AU  - Ferorelli P.
AU  - De Martino A.
AU  - Antonelli F.
AU  - Beninati S.
Y1  - 2013/02/20
PY  - 2013
N1  - https://doi.org/10.11648/j.ajls.20130101.14
DO  - 10.11648/j.ajls.20130101.14
T2  - American Journal of Life Sciences
JF  - American Journal of Life Sciences
JO  - American Journal of Life Sciences
SP  - 22
EP  - 26
PB  - Science Publishing Group
SN  - 2328-5737
UR  - https://doi.org/10.11648/j.ajls.20130101.14
AB  - A mixture of antioxidants found in a commercial food supplement called Citozym (CIZ), showed a preventive capability on experimental prostate hyperplasia induced by testosterone propionate (TP) in C57BL6/N mice. Treatments by CIZ were given orally and started 10 days before the induction of prostate hyperplasia. TP significantly increased prostate size and weight ratio, and this induced increase was significantly inhibited in CIZ-treated mice in comparison with positive controls in a dose-dependent manner. We conclude that CIZ can prevent TP-induced prostate hyperplasia and therefore may be beneficial in the management of benign prostatic hyperplasia.
VL  - 1
IS  - 1
ER  -

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Author Information

Torricelli P.

Department SPES, University of Molise, Campobasso, Italy
Ferorelli P.

University of Rome, Tor Vergata, Dept Biology, Roma, Italy
De Martino A.

University of Rome, Tor Vergata, Dept Biology, Roma, Italy
Antonelli F.

University of Rome, Tor Vergata, Dept Biology, Roma, Italy
Beninati S.

University of Rome, Tor Vergata, Dept Biology, Roma, Italy

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APA Style

Torricelli P., Ferorelli P., De Martino A., Antonelli F., Beninati S. (2013). Preventive Effects of A Mixture of Micronutrients with Antioxida-tive Properties on Experimentally Induced Prostate Hyperplasia. American Journal of Life Sciences, 1(1), 22-26. https://doi.org/10.11648/j.ajls.20130101.14

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ACS Style

Torricelli P.; Ferorelli P.; De Martino A.; Antonelli F.; Beninati S. Preventive Effects of A Mixture of Micronutrients with Antioxida-tive Properties on Experimentally Induced Prostate Hyperplasia. Am. J. Life Sci. 2013, 1(1), 22-26. doi: 10.11648/j.ajls.20130101.14

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AMA Style

Torricelli P., Ferorelli P., De Martino A., Antonelli F., Beninati S. Preventive Effects of A Mixture of Micronutrients with Antioxida-tive Properties on Experimentally Induced Prostate Hyperplasia. Am J Life Sci. 2013;1(1):22-26. doi: 10.11648/j.ajls.20130101.14

Copy | Download

@article{10.11648/j.ajls.20130101.14,
  author = {Torricelli P. and Ferorelli P. and De Martino A. and Antonelli F. and Beninati S.},
  title = {Preventive Effects of A Mixture of Micronutrients with Antioxida-tive Properties on Experimentally Induced Prostate Hyperplasia},
  journal = {American Journal of Life Sciences},
  volume = {1},
  number = {1},
  pages = {22-26},
  doi = {10.11648/j.ajls.20130101.14},
  url = {https://doi.org/10.11648/j.ajls.20130101.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.20130101.14},
  abstract = {A mixture of antioxidants found in a commercial food supplement called Citozym (CIZ), showed a preventive capability on experimental prostate hyperplasia induced by testosterone propionate (TP) in C57BL6/N mice. Treatments by CIZ were given orally and started 10 days before the induction of prostate hyperplasia. TP significantly increased prostate size and weight ratio, and this induced increase was significantly inhibited in CIZ-treated mice in comparison with positive controls in a dose-dependent manner. We conclude that CIZ can prevent TP-induced prostate hyperplasia and therefore may be beneficial in the management of benign prostatic hyperplasia.},
 year = {2013}
}

Copy | Download

TY  - JOUR
T1  - Preventive Effects of A Mixture of Micronutrients with Antioxida-tive Properties on Experimentally Induced Prostate Hyperplasia
AU  - Torricelli P.
AU  - Ferorelli P.
AU  - De Martino A.
AU  - Antonelli F.
AU  - Beninati S.
Y1  - 2013/02/20
PY  - 2013
N1  - https://doi.org/10.11648/j.ajls.20130101.14
DO  - 10.11648/j.ajls.20130101.14
T2  - American Journal of Life Sciences
JF  - American Journal of Life Sciences
JO  - American Journal of Life Sciences
SP  - 22
EP  - 26
PB  - Science Publishing Group
SN  - 2328-5737
UR  - https://doi.org/10.11648/j.ajls.20130101.14
AB  - A mixture of antioxidants found in a commercial food supplement called Citozym (CIZ), showed a preventive capability on experimental prostate hyperplasia induced by testosterone propionate (TP) in C57BL6/N mice. Treatments by CIZ were given orally and started 10 days before the induction of prostate hyperplasia. TP significantly increased prostate size and weight ratio, and this induced increase was significantly inhibited in CIZ-treated mice in comparison with positive controls in a dose-dependent manner. We conclude that CIZ can prevent TP-induced prostate hyperplasia and therefore may be beneficial in the management of benign prostatic hyperplasia.
VL  - 1
IS  - 1
ER  -

Copy | Download